The levels of insulin-like growth factor-1 and vascular endothelial growth factoraccording to clinical characteristics.

1Data are numbers of patients. Numbers in parentheses are percentages.2Data are median values, with the interquartile range (IQR) in parentheses.3Clinical cirrhosis was defined as having either one of the following: (i) presence of cirrhosis-related complications including ascites, varices, encephalopathy and/or (ii) radiographic evidence of small-sized or nodularliver with or without splenomegaly.4According to American Joint Committee on Cancer staging system (7th edition, 2010).AFP = α-fetoprotein, BCLC = Barcelona Clinic Liver Cancer, CLIP = Cancer of the Liver Italian Program, HBsAg = hepatitis B surface antigen, HCV = hepatitis C virus, NBNC = HBsAg- and anti-hepatitis C virus-negative.