Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide Descriptor: 2-(5-AMINO-6-OXO-2-M-TOLYL-6H-PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-ACETAMIDE, Coagulation factor XI, SULFATE ION Authors: Nagafuji, P, Jin, L, Rynkiewicz, M, Quinn, J, Bibbins, F, Meyers, H, Babine, R.E, Strickler, J.E, Abdel-Meguid, S.S. Deposit date: 2005-05-27 Release date: 2006-05-09 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Pyrimidinone Inhibitors of a Thrombolytic Protease To be Published

凝血因子XI（Coagulation Factor XI）催化结构域与2-(5-氨基-6-氧代-2-间甲苯基-6H-嘧啶-1-基)-N-[4-胍基-1-(噻唑-2-羰基)-丁基]-乙酰胺复合物的晶体结构
描述符：2-(5-氨基-6-氧代-2-间甲苯基-6H-嘧啶-1-基)-N-[4-胍基-1-(噻唑-2-羰基)-丁基]-乙酰胺、凝血因子XI、硫酸根离子（SULFATE ION）
作者：Nagafuji, P、Jin, L、Rynkiewicz, M、Quinn, J、Bibbins, F、Meyers, H、Babine, R.E、Strickler, J.E、Abdel-Meguid, S.S.
提交日期：2005-05-27
发布日期：2006-05-09
最后修改日期：2024-12-25
实验方法：X射线衍射（2.5 Å）
引用文献：《溶栓蛋白酶的嘧啶酮抑制剂》（Pyrimidinone Inhibitors of a Thrombolytic Protease），待发表