Association between family history risk categories and insulin secretion and resistance.

Note: Variables are presented as the range of median to quartile. ΔI30/ΔG30 = (INS30 - FINS)/(PG30 - FPG); ISI = 10,000/√(fasting plasma glucose [mmol/L] × fasting insulin [mU/L]) × (mean OGTT glucose [mmol/L] × mean OGTT insulin [mU/L]); DI = CIR × ISI; DI30 = ΔI30/ΔG30 × ISI CIR: corrected insulin response; DI: disposition index; DM: diabetes mellitus; FH0: negative family history of diabetes; FH1: moderate family history risk category of diabetes; FH2: high family history risk category of diabetes; FINS: fasting plasma insulin; FPG: fasting plasma glucose; HOMA-IR: homeostatic model assessment-estimated insulin resistance; INS30: serum insulin level at 30 min after OGTT; ISI: insulin sensitivity index; NGT: normal glucose tolerance; OGTT: oral glucose tolerance test; PG30: plasma glucose level at 30 min after OGTT. Association between family history risk categories and insulin secretion and resistance.