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Six-Step Method Followed for the Development and Validation of the Nef-ASI Tool. To facilitate testing of the Nef-ASI, a dedicated online platform was developed with access limited to the assessors. Abbreviations: cNF for cutaneous neurofibromas, HCP for healthcare professionals, ICC for intraclass correlation coefficient, MD for medical doctor. Supplemental material for the manuscript entitled "Measurement of the severity related to cutaneous neurofibromas in neurofibromatosis type 1: development and validation of the Nef-ASI", published in the Journal of the American Academy of Dermatology.

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2025-09-25
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