Diastereoselective Control of Intramolecular Aza-Michael Reactions Using Achiral Catalysts
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https://figshare.com/articles/dataset/Diastereoselective_Control_of_Intramolecular_Aza_Michael_Reactions_Using_Achiral_Catalysts/2597749
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资源简介：
An intramolecular aza-Michael reaction with a Cbz carbamate and an enone is reported to result in 3,5-disubstituted nitrogen-containing heterocycles. Either cis or trans isomers were obtained selectively using chiral substrates and an achiral Pd (II) complex or strong Brønsted acid catalysis. A range of substrates undergoes these selective transformations. Functionalization of the resulting products yielding bicyclic heterocycles is also demonstrated.
创建时间：
2011-10-21
