Genetic-to-epigenetic Therapy for Pancreatic Cancer
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE97215
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资源简介：
We utilized RNA-Seq to define molecular markers for the effect of chaetocin and MLN8237 combination. PDAC cells were treated with individual drugs or their combination and compared to vehicle. Treatment was limited to 24 hours to extract RNA before significant mitotic catastrophe occurred to capture the transcriptional effect. PANC-1 mRNA profiles following 24 hrs of treatment with vehicle (DMSO), chaetocin (30nM), MLN8237 (90nM) or a combination of chaetocin(30nM)+MLN3237(90nM). Each condition was performed in triplicate.
创建时间：
2019-08-01
