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Predicting drug response in human prostate cancer from preclinical analysis of in vivo mouse models (I)

ChEBI2015-09-17 更新2026-07-12 收录

前列腺癌药物研究

临床前动物模型预测

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69211 数据链接链接失效反馈

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Predicting drug response in human prostate cancer from preclinical analysis of in vivo mouse models (I)

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创建时间：

2015-09-17

前列腺癌药物研究

RORg反向激动剂

Work published by Wang et al. described pharmacological inhibition of RORg with an inverse agonist (SR2211) which led to a decrease in AR gene expression and a reduction in AR protein, which led to th

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RNA oligonucleotide sequences.

前列腺癌药物研究

转录组研究

The increasing incidence of prostate cancer (PCa) indicates an urgent need for the development of new effective drug therapy. There are limited options to treat the PCa, this study tried to determine

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The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer

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Aberrant activation of the androgen receptor (AR) plays a key role in the progression of prostate cancer. Current strategies to ablate AR signalling are circumvented when castration resistant prostate

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Siomycin A treatment in prostate cancer cell lines PC3 and LNCaP. Homo sapiens

前列腺癌药物研究

细胞周期基因

Siomycin A treatment in prostate cancer cell lines resulted in a concurrent inhibition of specific cell cycle genes and strongly impaired cell viability. Overall design: Illumina microarray experiment

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Synthesis of D‑Ring Annulated Pyridosteroids from β‑Formyl Enamides and Their Biological Evaluations

抗癌药物化学

前列腺癌药物研究

Herein, we report the synthesis of a novel class of substituted androst[17,16-b]pyridines (pyridosteroids) from the reaction of β-formyl enamides with alkynes in high yields. The optimized reaction

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Predicting drug response in human prostate cancer from preclinical analysis of in vivo mouse models (I)

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