Additional file 7: of In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

SNPs and Indels between the consecutive t012 and t021Â S. aureus isolates within the timespan between 1995 and 2008. The pairwise comparisons of the respective samples are listed in separate tabs and named accordingly. For each mutation, the nucleic acid changes and their position in relation to the genome sequence of t012#95 are given as well as the changes on amino acid level. Synonymous mutations are highlighted in green, non-synonymous mutations are marked in blue. A â *â displays a nonsense mutation (Stop). The changed nucleotide is highlighted in red. Deletions are labelled with a triangle; insertions are indicated by a plus. In addition, the orientation and if known, gene functions are given. Each tab contains the pairwise comparison of two consecutive isolates and is named accordingly. If there were no variants called, the table remained empty. The variants were detected with the program Breseq 0.27.1 (Deatherage and Barrick, 2014). NA, not applicable. (XLSX 131 kb)