Additional file 1 of Causal effect of gut microbiota and diabetic nephropathy: a Mendelian randomization study

Additional file 1: Supplementary Table S1. MR analysis results of casual links between significant gut microbiota and DN. Table S2. Selected and proxy SNPs for each significant gut microbiota. Table S3. Reverse MR analysis of DN on GM. Table S4. Sensitivity analysis for reverse MR analysis. Table S5. Mapped gene by all significant bacterial taxa related SNPs. Table S6. Transcriptome MR results of causality of mapped genes and DN. Table S7. Heterogeneity and pleiotropy test results for transcriptomic analysis.

附加文件1：补充表S1。显著肠道菌群与糖尿病肾病（Diabetic Nephropathy, DN）之间因果关联的孟德尔随机化（Mendelian Randomization, MR）分析结果。表S2：各显著肠道菌群对应的筛选单核苷酸多态性及代理单核苷酸多态性（Single Nucleotide Polymorphism, SNPs）位点。表S3：糖尿病肾病（DN）对肠道菌群（Gut Microbiota, GM）的反向孟德尔随机化分析结果。表S4：反向孟德尔随机化分析的敏感性检验结果。表S5：所有显著细菌类群相关单核苷酸多态性位点所映射的基因。表S6：映射基因与糖尿病肾病（DN）之间因果关联的转录组孟德尔随机化分析结果。表S7：转录组分析的异质性与多效性检验结果。