LieberInstitute/spatial_DG_lifespan: v1.0.0
收藏资源简介:
The Github repository contains a variety of scripts that can be run on the SpatialExperiment object e.g., for quality control, unsupervised spatial clustering, pseudo-bulking data, differential expression, and surveying of gene sets from other publications.Here, we include two SpatialExperiment S4 Class storage (spe) objects. The basic spe object stores the raw counts for all the Visium experiments and metadata. The processed spe object is after quality control, batch correction, data integration, unsupervised spatial clustering, cell-type deconvolution, and also contains the metadata.Also included are compressed files for the raw images of haematoxylin and eosin-stained tissue for each Visium slide.
本GitHub仓库包含多款可针对空间实验对象(SpatialExperiment)运行的脚本,可用于质量控制、无监督空间聚类、伪批量数据处理、差异表达分析,以及检索其他已发表文献中的基因集。本次仓库收录了两个S4类空间实验对象(SpatialExperiment,以下简称spe):其中基础spe对象存储了所有Visium实验的原始计数矩阵与元数据;经过处理的spe对象则完成了质量控制、批次校正、数据整合、无监督空间聚类及细胞类型反卷积流程,同样附带元数据。仓库还收录了每一张Visium玻片对应的苏木精-伊红染色组织原始图像的压缩文件。



