Data from: The incidence of admissions for schizophrenia and related psychoses in two cohorts: 1875-1924 and 1994-2010

OBJECTIVES: To investigate changes in incidence of admissions for schizophrenia and related non-affective psychoses in North Wales. DESIGN: Data from two epidemiologically complete cohorts of patients presenting for the first time to mental health services in North Wales between 1875-1924 and 1994-2010 are used in this study to map the incidence of hospital admissions for schizophrenia and non-affective psychoses. SETTING: The North Wales Asylum Denbigh (archived patient case notes) and the North West Wales District General Hospital psychiatric unit. POPULATION: 3168 patients admitted to the North Wales Asylum Denbigh 1875-1924 and 355 patients admitted to the District General Hospital psychiatric unit 1994-2010. RESULTS: There was an increasing admission incidence for schizophrenia between 1875 and 1900, a higher admission rate in the 1990s for males, followed by a drop in rates of admission for both genders since 2006. Admission incidences switch from parity between the sexes in the historical period to a doubling of the admission rates for men compared to women in the modern period. This admission pattern differs from the admission patterns for affective psychoses or organic disorders. CONCLUSION: There have been changes in the incidence of admissions for schizophrenia in North Wales.

研究目标：探究北威尔士地区精神分裂症（schizophrenia）及相关非情感性精神病（non-affective psychoses）的住院收治率变化情况。
研究设计：本研究纳入两组流行病学完整队列数据，分别为1875年至1924年、1994年至2010年期间北威尔士地区首次就诊于精神卫生服务机构的患者，以此绘制精神分裂症及非情感性精神病的住院收治率变化图谱。
研究地点：北威尔士登比郡精神病院（存档患者病历）及西北威尔士地区综合医院精神科病房。
研究人群：1875年至1924年间收治于北威尔士登比郡精神病院的3168例患者，以及1994年至2010年间收治于该综合医院精神科病房的355例患者。
研究结果：1875年至1900年间，精神分裂症的住院收治率呈上升趋势；20世纪90年代男性收治率高于女性，自2006年起两性收治率均出现下降。历史队列中两性收治率基本持平，而现代队列中男性收治率较女性升高一倍。该收治模式与情感性精神病（affective psychoses）或器质性障碍（organic disorders）的收治模式存在差异。
研究结论：北威尔士地区精神分裂症住院收治率已发生变化。