Self-adjuvanting Nanovaccines Boost Lung-resident CD4+ T Cell Immune Responses in BCG-primed mice

The "readcount_genename.xls" file and "fpkm_genename.xls" file contain gene expression data for genes (gene list is detailed in "gene.xls") in the panel. All data were obtained from bone marrow derived dendritic cells from WT C57BL/6 mice treated with KFE8 nanofibers or mock. All RNA sequencing and subsequent processing was performed by Novogene Corporation. The remaining .xls files contain the differential expression analysis for KFE8 nanofiber treatment at four hours compared with mock (NF4vsC4) or KFE8 nanofiber treatment at sixteen hours compared with mock (NF16vsC16). The "pathway analysis Rcode.R" file contains the code used to generate Reactome pathway analysis for both time points. The "NF16 volc Rcode.R" file contains the code used to generate a volcano plot for the 16 hour time point.文件"readcount_genename.xls"与"fpkm_genename.xls"包含本研究面板内所有基因的基因表达数据，基因列表详见"gene.xls"。所有数据均来源于经KFE8纳米纤维（KFE8 nanofibers）或模拟处理（mock）的野生型C57BL/6小鼠骨髓来源树突状细胞。所有RNA测序及后续分析流程均由诺禾致源公司（Novogene Corporation）完成。剩余的.xls文件分别包含两组差异表达分析结果：一组为KFE8纳米纤维处理4小时组与模拟处理组的比较（命名为NF4vsC4），另一组为KFE8纳米纤维处理16小时组与模拟处理组的比较（命名为NF16vsC16）。文件"pathway analysis Rcode.R"包含用于生成两个时间点Reactome通路分析结果的代码；文件"NF16 volc Rcode.R"则包含用于生成16小时时间点火山图的代码。