Additional file 2 of Association between polygenic risk for Alzheimer’s disease and brain structure in children and adults

Additional file 2: Table S1. Descriptive details about study sample. Table S2. Number of SNPs at each p-value inclusion threshold. Table S3. A comprehensive list of all MRI metrics examined in our study. Table S4. Interaction of PRS-hemisphere for regional cortex (CA, CT, CV). Table S5. Interaction of PRS-hemisphere for white matter tracts (FA, MD). Table S6. Interaction of PRS-hemisphere for subcortical volume (SV). Table S7.Results for association between all eight PRS and regional cortex (CA, CT, CV). Table S8. Results for association between all eight PRS and subcortical volume (SV). Table S9. Results for association between all eight PRS and whitematter tracts (FA, MD). Table S10. Sensitivity analysis results (ABCD -(Kunkle et al. 2019)) for association between all eight PRS and regional cortex (CA, CT, CV). Table S11. Sensitivity analysis results (ABCD -(Kunkle et al. 2019)) for association between all eight PRS and subcortical volume(SV). Table S12. Sensitivity analysis results (ABCD - (Kunkle et al.2019)) for association between all eight PRS and white matter tracts (FA, MD). Table S13. Results for association between all eight PRS (excluding APOE along with adjust APOE genotype) and regional cortex(CA, CT, CV). Table S14. Results for association between all eight PRS (excluding APOE along with adjust APOE genotype) and subcortical volume (SV). Table S15. Results for association between all eight PRS (excluding APOE along with adjust APOE genotype) and whitematter tracts (FA, MD). Table S16. Sensitivity analysis results (UKB -adjust 40PCs) for association between all eight PRS and regional cortex (CA, CT, CV). Table S17. Sensitivity analysis results (UKB - adjust 40PCs) for association between all eight PRS and subcortical volume (SV). Table S18.Sensitivity analysis results (UKB - adjust 40PCs) for association between all eight PRS and white matter tracts (FA, MD). Table S19. Sensitivity analysis results (ABCD - adjust birth weight and gestational age) for association between all eight PRS and regional cortex (CA, CT, CV). Table S20. Sensitivity analysis results (ABCD - adjust birth weight andgestational age) for association between all eight PRS and subcortical volume(SV). Table S21. Sensitivity analysis results (ABCD - adjust birthweight and gestational age) for association between all eight PRS and whitematter tracts (FA, MD). Table S22. Sensitivity analysis results (outliers winsorized) for association between all eight PRS and regional cortex (CA, CT, CV). Table S23. Sensitivity analysis results (outliers winsorized) for association between all eight PRS and subcortical volume (SV). TableS24. Sensitivity analysis results (outliers winsorized) for association between all eight PRS and white matter tracts (FA, MD).