Circadian transcriptome of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO and control Cre- littermates

To investigate the role of the circadian clock gene Bmal1 in skeletal muscle, we compared the circadian transcriptomes of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO (mKO) and their control Cre- littermates (Ctrl). Keyword: Circadian Transcriptome, time course 72 samples were analyzed, comprised of 4 experimental groups (Ctrl SOL, mKO SOL, Ctrl TA, mKO TA), with 3 biological replicates for each time point sampled every 4 hours for 24 hours. SOL and TA muscles were collected from the same animals, as indicated by Source Animal ID data column为探究生物钟基因Bmal1在骨骼肌中的作用，我们对比了肌肉特异性Bmal1敲除（muscle-specific Bmal1 KO，mKO）小鼠的快肌胫骨前肌（tibialis anterior，TA）与慢肌比目鱼肌（soleus，SOL）的昼夜转录组，并以其Cre-同窝对照小鼠（Ctrl）作为对照。 关键词：昼夜转录组（Circadian Transcriptome）、时间进程（time course） 本数据集共分析72份样本，涵盖4个实验组（Ctrl SOL、mKO SOL、Ctrl TA、mKO TA），每个时间点设置3次生物学重复，采样间隔为4小时，总采样时长为24小时。 如"来源动物ID"数据列所示，比目鱼肌与胫骨前肌均采自同一实验动物。