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The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

ChEBI2009-03-08 更新2026-07-21 收录

拷贝数变异与基因表达关联

造血干细胞组学研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-10656 数据链接链接失效反馈

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The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

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2009-03-08

神经母细胞瘤候选基因发现

拷贝数变异与基因表达关联

Gene expression analysis was performed on 30 Neuroblastomas to identify genes whose transcription is significantly altered by recurrent chromosomal alterations. Genomic copy number losses and gains ha

NIAID Data Ecosystem70

The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

拷贝数变异与基因表达关联

造血干细胞表达调控

The extent to which differences in germ line DNA copy number contribute to natural phenotypic variation is unknown. We analyzed the copy number content of the mouse genome to a sub-10 kb resolution. W

NIAID Data Ecosystem20

Integrated analysis of differences in gene expression and copy number between Proneural GBM and Proneural Oligodendroglioma/Astrocytoma samples.

胶质瘤分子亚型分析

拷贝数变异与基因表达关联

Loci with amplification or deletion and corresponding changes in gene expression in Proneural GBM or Proneural Oligodendrogliomas/Astrocytomas are shown.

NIAID Data Ecosystem10

Additional file 4: Table S4. of Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study

癌症基因组数据

拷贝数变异与基因表达关联

Functional enrichment results of 81 tumor suppress genes (TSGs) with decreased gene expression potentially induced by copy number losses (CNLs). (XLSX 24 kb)

Figshare2016-12-16 更新40

CNV categories that were investigated for role in transcriptional expression.

拷贝数变异与基因表达关联

转录调控

Three classes of CNVs were investigated. The WTCCC CNVs were divided into two groups, according to whether they were tagged (r2≥0.80) by a local (i.e., within 1 MB) SNP from imputed WTCCC1 data and ge

NIAID Data Ecosystem10

The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

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