HumanViCe
收藏资源简介:
HumanViCe provides the users with the potential ceRNA networks in virus infected human cells that are instrumental in fine tuning of gene expressions to aid the host defense against viruses. HumanViCe curretly ghouses a total of 144 viral miRNAs encoded by 10 viruses known to infect human cells, which target 6,257 human lncRNA transcripts (with GENCODE 19 as the reference) and 1,277 human circRNA transcripts. It calculates a ceRNA score for each potential ceRNA pair to show the likelihood for them to act as ceRNAs.
HumanViCe可为用户提供病毒感染人类细胞内的潜在内源竞争RNA(ceRNA)调控网络,此类网络可通过精准微调基因表达,助力宿主抵御病毒感染。目前,HumanViCe收录了10种已知可感染人类的病毒所编码的共计144条病毒微RNA(miRNA),这些病毒miRNA可靶向结合6257条人类长链非编码RNA(lncRNA)转录本(以GENCODE 19作为参考基因组)以及1277条人类环状RNA(circRNA)转录本。该数据集会为每一对潜在ceRNA对计算ceRNA评分,以反映二者作为ceRNA发挥功能的可能性。




