Hadha

ENCODES a protein that exhibits 3-hydroxyacyl-CoA dehydratase activity; 3-hydroxyacyl-CoA dehydrogenase activity; acetyl-CoA C-acyltransferase activity; INVOLVED IN fatty acid beta-oxidation; response to xenobiotic stimulus; cardiolipin acyl-chain remodeling (ortholog); PARTICIPATES IN fatty acid metabolic pathway; carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; ASSOCIATED WITH Fetal Growth Retardation; metabolic dysfunction-associated steatotic liver disease; Alzheimer's disease (ortholog); FOUND IN mitochondrial fatty acid beta-oxidation multienzyme complex; mitochondrial inner membrane (ortholog); mitochondrial nucleoid (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol

编码一种具有3-羟基酰基辅酶A脱氢酶活性、3-羟基酰基辅酶A脱氢酶活性、乙酰辅酶A C-酰基转移酶活性的蛋白质；参与脂肪酸β-氧化、对异物刺激的反应、心磷脂酰链重塑（同源物）；参与脂肪酸代谢途径、肉碱棕榈酰转移酶I缺乏途径、乙基琥珀酸脑病途径；与胎儿生长迟缓、代谢功能障碍相关脂肪性肝病、阿尔茨海默病（同源物）相关；存在于线粒体脂肪酸β-氧化多酶复合物中、线粒体内膜（同源物）、线粒体核区（同源物）；与（+）五味子素B、17α-乙炔雌二醇、17β-雌二醇相互作用。