Summery statistics from GWAS data for 425 plasma protein biomarkers

Summary statistics from an association study comparing the concentration levels of 425 plasma proteins with the genome-wide genetic variation. Statistically significant associations from this data has previously been published in: "Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases" by Enroth et al in Scientific Reports 2018 (https://www.nature.com/articles/s41598-018-23860-y, also included here as "s41598-018-23860-y.pdf") Each library file contains 24 files (chr1-22, X, M) with the associations of genetic markers to the protein given in the name of the library file. A list of matches between protein identifiers can be found in the "proteinInfo.txt" file. All coordinates are given in the hg19 assembly.本关联研究针对425种血浆蛋白的浓度水平与全基因组遗传变异展开对比分析，本次发布的为该研究的汇总统计数据。 基于该数据筛选得到的具有统计学显著性的遗传关联结果，此前已发表于： 《降压与降脂药物对心血管疾病血浆蛋白生物标志物的系统性及特异性影响》，作者Enroth等，发表于2018年《Scientific Reports》（链接：https://www.nature.com/articles/s41598-018-23860-y，本文数据集同时收录该文献的PDF版本，文件名为"s41598-018-23860-y.pdf"） 每个库文件内含24个分文件（对应chr1至chr22、X染色体及线粒体基因组M），用于存储遗传标记与库文件名所指定蛋白的关联分析结果。 蛋白标识符的匹配对照表可于"proteinInfo.txt"文件中查阅。所有基因组坐标均采用hg19参考基因组组装版本。