Location of antigenic sites and informative sites on dengue type 3 E protein.

1The amino acids that form each domain of DENV3 E protein are according to Modis et al [12]. 2The antigenic regions are based on the assignments and nomenclature used by Pierson et al [19]. 3Based on Roehrig and Pierson [10],[19].The numbering is based on the DENV3 E protein sequence. 4DENV3 E protein informative sites were identified as described in Figure 1.