Living kidney donor evaluation is associated with early identification of life‐changing diagnoses in potentially healthy donor candidates

Background: In order to ensure eligibility for living kidney donation, donor candidates undergo a thorough medical evaluation. This process might reveal hitherto undetected medical conditions, leading to refusal of the kidney donor candidate. Detection of such conditions may, however, also have a lifesaving effect. We report on 13 years of data from our living donor transplantation program on kidney donor candidates who were diagnosed with major medical conditions during evaluation.
Materials and Methods: We performed a retrospective analysis of living kidney donor candidates who attended our transplant center between 01/2007 and 12/2019. The main focus was on newly diagnosed medical conditions that required immediate medical attention and their prognostic significance.
Results: Of the 436 donor candidates who were evaluated for living kidney donation at our transplant center, 192 (44%) were accepted, while 244 (56%) were excluded from donation. Interestingly, 81 (33.1%) of the ineligi...

背景：为确保活体肾脏捐献的合规性，潜在捐献者需接受全面的医学评估。该评估过程可能发现此前未被检出的疾病，进而导致该肾脏捐献候选者被拒绝。然而，检出此类疾病也可能起到挽救生命的作用。本研究报告了本中心活体捐献移植项目13年间的相关数据，对象为评估期间被诊断出重大疾病的肾脏捐献候选者。
材料与方法：本研究对2007年1月至2019年12月期间在本移植中心就诊的活体肾脏捐献候选者进行了回顾性分析。研究重点为需要立即就医的新诊断疾病及其预后意义。
结果：在本移植中心接受活体肾脏捐献评估的436名候选者中，192名（44%）获得捐献资格，244名（56%）被排除捐献资格。值得注意的是，在被排除的244名候选者中，有81例（33.1%）的……