The protein-protein interactions of AKT1-E17K or AKT1 wild type detected using the NanoLuc luciferase-based bioluminescence resonance energy transfer (BRETn) technology-based quantitative high-through
ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); ATP binding (ortholog); calmodulin binding (ortholog); INVOLVED IN insulin receptor signaling pathway; phosphatidylinositol 3-kinase/
In the mammalian heart AKT1 and AKT2 are the isoforms of the protein kinase AKT (protein kinase B) which are predominantly expressed. AKT isoforms exert common and specific functions in the field of m