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Insertion of Arynes into Thioureas: A New Amidine Synthesis

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https://figshare.com/articles/dataset/Insertion_of_Arynes_into_Thioureas_A_New_Amidine_Synthesis/2613763
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Arynes, generated from trimethylsilyl phenyltriflate precursors, have been found to react with thioureas via a formal π-insertion into the CS bond. The reaction contrasts with that of ureas, which proceeds via benzyne σ-insertion into the C–N bond, and represents a new, operationally simple route to functionalized amidines.
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2016-02-22
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