Hippocampal LFP analysis in rats treated with reserpine (Fibromyalgia model)

Dataset obtained in the analysis of chronic recordings of local field potential of the dorsal hippocampus in SD rats trated with IP reserpine (fibromyalgia model). Used in the journal paper: Hippocampal oscillatory dynamics and sleep atonia are altered in an animal model of fibromyalgia: Implications in the search for biomarkersArantxa Blasco-Serra, Gloria Alfosea-Cuadrado, Ana Cervera-Ferri, Eva M González-Soler, Ana Lloret , Joana Martínez-Ricós, Vicent Teruel-Martí, Alfonso A Valverde-NavarroDOI: 10.1002/cne.24829 Description of the dataset: Specimen: code of the animal Status: control (before reserpine administration), reserpina (following reserpine administration) Statuscompl: control (before reserpine administration), PR (days following reserpine administration, i.e 13PR = 13 days folloing reserpine administration) Day: recorging day ti and tf: inicial and end time of the window analyzed Spectral analysis: band power and band ratio of the frequency bands (Hz): b1=[0.3 1.5]; b2=[1.5 4]; b3=[4 12]; b4=[12 16]; b5=[16 30]; b6=[30 80]; b7=[80 125]; band=[0.3 125]; Wavelet analysis: detection of regions with predominance of slow waves (b1) and theta (b3) b3_regions b3_ratio b3_meanfreq b3_std b3_width b3_fragmentation b1_regions b1_ratio b1_meanfreq b1_std b1_width b1_fragmentation EEMG analysis: mean value and standard deviation of the RMS EMG (EMGmean EMGstd) Sleep stage: determination of the sleep stage from EMG, slow waves, delta and theta results. Transitions: periods with diferent sleep stage from the precedent.本数据集来源于对经腹腔注射（intraperitoneal, IP）利血平构建纤维肌痛模型的SD大鼠背侧海马局部场电位（local field potential, LFP）所开展的慢性记录分析。本数据集配套发表于以下期刊论文：《纤维肌痛动物模型中海马振荡动力学与睡眠失张力发生改变：生物标志物探索的启示》，作者：Arantxa Blasco-Serra、Gloria Alfosea-Cuadrado、Ana Cervera-Ferri、Eva M González-Soler、Ana Lloret、Joana Martínez-Ricós、Vicent Teruel-Martí、Alfonso A Valverde-Navarro，DOI: 10.1002/cne.24829。 数据集详细说明如下： 1. 标本：实验动物的编号代码 2. 分组状态：分为对照组（利血平给药前）、利血平给药组 3. 分组补充说明：对照组为利血平给药前样本，PR组指代利血平给药后的天数，例如13PR代表利血平给药后13天 4. 记录天数：本次实验的记录当日序号 5. ti与tf：待分析窗口的起始时刻与终止时刻 6. 频谱分析：针对各频率频段（单位：Hz）计算带功率与带比值，具体频段设置如下： b1=[0.3 1.5]; b2=[1.5 4]; b3=[4 12]; b4=[12 16]; b5=[16 30]; b6=[30 80]; b7=[80 125]; 全频段范围为band=[0.3 125]。 7. 小波分析：用于检测以慢波（对应b1频段）和θ波（对应b3频段）占主导的脑区区域，提取的特征指标包括：b3_regions、b3_ratio、b3_meanfreq、b3_std、b3_width、b3_fragmentation、b1_regions、b1_ratio、b1_meanfreq、b1_std、b1_width、b1_fragmentation。 8. 肌电图（electromyography, EMG）分析：计算肌电均方根（root mean square, RMS）的均值与标准差，对应特征为EMGmean、EMGstd。 9. 睡眠时相判定：基于肌电信号、慢波、δ波与θ波的分析结果确定动物的睡眠时相。 10. 睡眠转换时段：与前一睡眠时相存在差异的时段。