A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.

ChEBI2014-08-15 更新2026-07-21 收录

mRNA无义介导降解

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60045 数据链接链接失效反馈

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A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.

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2014-08-15

RPL12 phosphorylation regulates translation during mitosis - pSILAC B cell PRM -

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有丝分裂翻译

project_description Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal p

NIAID Data Ecosystem70

The Upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation

mRNA无义介导降解

病毒基因表达调控

The nonsense-mediated mRNA decay pathway functions to degrade aberrant mRNAs that contain premature translation termination codons. In Saccharomyces cerevisiae, the Upf1, Upf2, and Upf3 proteins have

PubMed Central1998-07-21 更新40

Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements

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表观遗传调控

Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3′UTR of Dnmt1 mRNA identic

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An Engineered Version of Human PON2 Opens the Way to Understand the Role of Its Post-Translational Modifications in Modulating Catalytic Activity

蛋白工程

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The human paraoxonase 2 (PON2) has been described as a highly specific lactonase hydrolysing the quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone (3OC12-HSL) and having secondary ester

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Additional file 1 of METTL3 drives NSCLC metastasis by enhancing CYP19A1 translation and oestrogen synthesis

癌症转移机制

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Supplementary Material 1 (Table S1–S4): Gene expression data correlated with clinical information, sequencing data, and mass spectometry data. Table S1: METTL3/CYP19A1 expression of TMA data from 84 N

NIAID Data Ecosystem40

A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.

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