PREDICTORS OF POST-OPERATIVE OUTCOME IN EMERGENCY LAPAROTOMY FOR PERFORATION PERITONITIS, A PROSPECTIVE CROSS-SECTIONAL STUDY

Introduction Surgical mortality is high in hollow viscus perforation. Numerous efforts have been undertaken to preoperatively identify high-risk individuals and to optimize and manage these patients with greater vigour. To assess the predictors of outcome for patients undergoing emergency laparotomy due to perforation peritonitis, this study was conducted. Techniques: This prospective cross-sectional study will be carried out on patients with perforation peritonitis who are admitted to tertiary care hospitals' Department of General Surgery. We assessed the relationship between preoperative patient characteristics and mortality, anastomotic leakage, postoperative problems, and the necessity for intensive care unit (ICU) admission. The study concludes that patients receiving emergency laparotomy for perforation peritonitis are more likely to have high mortality after surgery if they have hypotension, azotemia, coagulopathy, or a delay in treatment. The identification of preoperative determinants of the requirement for ICU admission is aided by this investigation. Finding preoperative indicators linked to a higher risk of postoperative problems is made easier by this study.引言 空腔脏器穿孔（hollow viscus perforation）患者的术后手术死亡率居高不下。学界已开展多项探索，旨在术前甄别高危人群，并以更为积极的诊疗策略优化此类患者的管理流程。为评估因穿孔性腹膜炎（perforation peritonitis）接受急诊剖腹手术（emergency laparotomy）患者的预后预测因素，本研究特此开展。 方法 本前瞻性横断面研究纳入了三级医院普通外科收治的穿孔性腹膜炎（perforation peritonitis）患者，分析患者术前基线特征与术后死亡率、吻合口漏（anastomotic leakage）、术后并发症（postoperative problems）及重症监护病房（Intensive Care Unit, ICU）收治需求之间的关联。 本研究结论表明，因穿孔性腹膜炎（perforation peritonitis）接受急诊剖腹手术（emergency laparotomy）的患者，若合并低血压、氮质血症（azotemia）、凝血功能障碍（coagulopathy）或治疗延迟，则术后死亡风险显著升高。本研究有助于明确与ICU收治需求相关的术前决定因素，同时也为识别术后并发症（postoperative problems）风险升高相关的术前指标提供了有效支持。