This file documents functional and pathway interpretation for differentially expressed genes using QIAGEN IPA according to [22].

File contains Diseases and Functions according to differential gene expression including p-values and molecules (T1); lists canonical pathways along with corresponding molecules, direction of expression and pathway activity predictions including p-values, z-score, ratio and molecules (T2); causal network analyses predicting upstream and downstream regulators and networks involving specific gene families including direction of activation or inhibition, p-value, and molecules (T3); lists predicted upstream regulators according to observed gene expression changes with corresponding p-values and molecules (T4); underlying network molecules and key diseases or functions used for Figure 3 included in the present manuscript detailing key molecules (T5). (XLSX)