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Hairpin Capture of DNA End Structures reveals chromosomal DNA end structure with single nucleotide resolution

ChEBI2014-12-03 更新2026-07-21 收录

DNA末端结构解析

单核苷酸分辨率基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62534 数据链接链接失效反馈

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资源简介：

Hairpin Capture of DNA End Structures reveals chromosomal DNA end structure with single nucleotide resolution

应用场景：

创建时间：

2014-12-03

"RNA研究"

单核苷酸分辨率基因组学

mRNAs of human and mouse cell lines were purified using oligo (dT)-conjugated magnetic beads followed by RiboMinus treatement. mRNAs were fragmented to ~100 nt and treated by Sodium bisulfite solution

NIAID Data Ecosystem100

Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing

活性DNA去甲基化

单核苷酸分辨率基因组学

Active DNA demethylation in mammals involves TET-mediated iterative oxidation of 5-methylcytosine (5mC)/5-hydroxymethylcytosine (5hmC) and subsequent excision repair of highly oxidized cytosine bases

NIAID Data Ecosystem100

Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice. Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice

DNA损伤修复机制

单核苷酸分辨率基因组学

In the present work we have applied analytical methods to map repair events in rDNA using data generated by the newly developed XR-seq genome-wide single nucleotide repair technology. We find that in

NIAID Data Ecosystem60

DEtail-seq profiled meiotic DSBs in Mus musculus

减数分裂DNA断裂检测

单核苷酸分辨率基因组学

SPO11-promoted DNA double-strand breaks (DSBs) formation is a crucial step for meiotic recombination, and it is indispensable to detect the broken DNA ends accurately for dissecting the molecular mech

NIAID Data Ecosystem100

Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution

细菌DNA甲基化

单核苷酸分辨率基因组学

In the bacterial world, methylation is most commonly associated with restriction-modification systems that provide a defense mechanism against invading foreign genomes. In addition, it is known that m

NIAID Data Ecosystem80

Hairpin Capture of DNA End Structures reveals chromosomal DNA end structure with single nucleotide resolution

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