Additional file 7 of A novel small molecule, AS1, reverses the negative hedonic valence of noxious stimuli

Additional file 7: Supplementary Table 2. Brain regions specifically upregulated in the context of 5 µM AS1 and noxious heat (37.5 °C). A complete list of all of the regions of interest (ROIs) identified from MAP-Mapping analysis of pERK/tERK-labeled brains of larval zebrafish that were incubated in 5 µM AS1 and exposed to noxious heat. The “Signal Specific to AS1 + Heat” was obtained by subtracting the net signals of the “AS1 Only” and “Heat Only” groups from the net signal of the “AS1 + Heat” group for each ROI. ROIs are ranked in order from highest to lowest signal.

附加文件7：补充表2。经5 µM AS1处理并暴露于伤害性热刺激（37.5℃）下特异性上调的脑区。本列表收录了经5 µM AS1孵育并暴露于伤害性热刺激的幼斑马鱼pERK/tERK标记脑区的MAP-Mapping分析中所鉴定出的全部感兴趣脑区（regions of interest, ROIs）。针对每个感兴趣脑区，“AS1+热刺激特异性信号”通过从“AS1联合热刺激”组的净信号中减去“仅AS1处理”组与“仅热刺激”组的净信号得到。感兴趣脑区按信号强度从高到低排序。