Expression array of DNMT1 inhibitor treated 3 AML cell lines
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134742
下载链接
链接失效反馈官方服务：
资源简介：
Genome wide demethylation by DNMT1 inhibitor GSK3484862 results in up-regulation of epigenetically-silenced genes Differential expression was perfomed for each cell line following DNMT1 inhibitor or vehicle treatment. Differentially epressed gene lists were submitted to gene set enrichment analysis (GSEA) to identify consistently changed pathways. Three AML cell lines were treated for 96 hours in biological duplicate with 0.1% DMSO, DNMT1 specific inhibitor 1 µM GSK3484862, or an inactive compound GSK3510477 before isolating RNA, labeling, and hybridizing to Affymetrix GeneChip® Human Genome U1331 Plus 2.0 arrays.
创建时间：
2023-01-02
