Identification of chromatin-associated proteins occupying the promoter region of CDKN1A
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https://www.omicsdi.org/dataset/pride/PXD022542
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资源简介：
The p21 protein, encoded by CDKN1A, plays a vital role in the induction of senescence, and its transcriptional control by p53 tumour supressor is well-established. However, p21 can also be regulated in a p53-independent manner, by mechanisms that remain poorly understood. Therefore, we here used a chromatin-directed proteomic approach and identified ZNF84 as a novel regulator of p21 in various p53-deficient cell lines.
创建时间：
2021-09-07
