Curated Antibiofilm, Quorum Sensing, and Random Peptide Datasets (ABFP, QSP, and RP Sets)
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This dataset compiles three curated peptide sets developed for the study “Mapping the Antibiofilm Peptide Space with Similarity Networks and Curated Negative Sets.”It includes: ABFPs (Antibiofilm Peptides): 387 experimentally validated antibiofilm peptides collected from 11 independent studies, including those annotated with MBIC, MBEC, and MBIC–MBEC values, reflecting their quantitative biofilm inhibition or eradication activity. QSPs (Quorum Sensing Peptides): 225 peptides involved in microbial communication and signaling pathways relevant to quorum sensing mechanisms. RPs (Random Peptides): 1,956 peptides generated as a compositionally neutral background to enable unbiased comparative analyses. All sequences are provided in FASTA format, with class identifiers (“ABFP”, “QSP”, and “RP”) at the beginning of each header to facilitate retrieval and automated processing.The dataset totals 2,568 peptide sequences and serves as a benchmark resource for machine learning, network analysis, and peptide activity prediction studies.
本数据集汇编了为研究《利用相似性网络与精选阴性集绘制抗生物膜肽图谱》(Mapping the Antibiofilm Peptide Space with Similarity Networks and Curated Negative Sets)开发的三组精选肽数据集。具体包含以下三类肽段: ABFPs(抗生物膜肽,Antibiofilm Peptides):387条经实验验证的抗生物膜肽,采集自11项独立研究,涵盖标注有最低生物膜抑制浓度(Minimum Biofilm Inhibitory Concentration,MBIC)、最低生物膜清除浓度(Minimum Biofilm Eradication Concentration,MBEC)及MBIC-MBEC值的肽段,可反映其定量的生物膜抑制或清除活性。 QSPs(群体感应肽,Quorum Sensing Peptides):225条参与微生物群体感应相关通信与信号通路的肽段。 RPs(随机肽,Random Peptides):1956条经生成得到的组成中性背景肽段,用于开展无偏比较分析。 所有序列均以FASTA格式提供,每条序列的标题开头均带有类别标识符("ABFP"、"QSP"及"RP"),以方便检索与自动化处理。本数据集总计包含2568条肽序列,可作为机器学习、网络分析及肽段活性预测研究的基准资源。



