Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P1211
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Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P1211 Descriptor: Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Li, T, Li, G.Y, Yin, H. Deposit date: 2021-08-23 Release date: 2022-07-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. Acs Catalysis, 12, 2022
来自市政热脆菌(*Thermocrispum municipale*)突变体L437T的环己酮单加氧酶(Cyclohexanone Monooxygenase)与烟酰胺腺嘌呤二核苷酸磷酸(NADP+,Nicotinamide-Adenine-Dinucleotide Phosphate)和黄素腺嘌呤二核苷酸(FAD,Flavin-Adenine Dinucleotide)结合的晶体结构,空间群为P12₁1。 数据集描述:市政热脆菌来源的环己酮单加氧酶、黄素腺嘌呤二核苷酸、烟酰胺腺嘌呤二核苷酸磷酸…… 作者:李涛(Li, T)、李光宇(Li, G.Y)、尹晗(Yin, H) 提交日期:2021年8月23日 发布日期:2022年7月6日 最后修改日期:2023年11月29日 实验方法:X射线衍射(分辨率2.08 Å) 引用文献:《生物催化拜耳-维利格反应:通过细致解析瞬态手性中间体,揭示突变体各进化阶段的区域选择性来源》,《ACS催化》,2022年,第12卷



