Conditioned place preference reveals ongoing pain in calves 3 weeks after disbudding

The authors initiated a retraction over concerns relating to irregularities found in the raw data. Concerns relating to the data can be found in the retraction notice: https://www.nature.com/articles/s41598-025-88692-z
Hot-iron disbudding, a routine procedure that prevents horn bud growth through cauterization, is painful for calves. The resulting burns remain sensitive to touch for weeks, but it is unknown whether calves experience ongoing, non-evoked pain. We evaluated conditioned place preference for analgesia in 44 calves disbudded or sham-disbudded 6 hours (Day 0) or 20 days (Day 20) before testing (n = 11/treatment). Calves were conditioned to associate the effects of a lidocaine cornual nerve block with the location and pattern of a visual stimulus, and a control injection of saline with the contrasting stimulus. On Day 0, disbudded calves tended to prefer the lidocaine-paired stimulus over the saline-paired one, suggesting that they found analgesia rewarding. On Day 20, sham cal..., These details are provided in the orginal article, but please note that this has been retracted. , We do not recommend use of these data. This article has been retracted. 
Data were collected from the University of California Davis Dairy Facility on 44 calves in 2017. Variables are defined in Sheet 2 of each Excel file. The R script used to analyze each dataset is provided., # Data from: Conditioned place preference reveals ongoing pain in calves 3 weeks after disbudding

[https://doi.org/10.25338/B8NS56](https://doi.org/10.25338/B8NS56)

## Description of the data and file structure

These are data and code from a conditioned place preference study with dairy calves. 
### Files and variables

#### File: Adcock\_Tucker\_2020\_Conditioning\_Trials\_Data\_Analysis.R

**Description:** R script for conditioning trials

#### File: Adcock\_Tucker\_2020\_Preference\_Test\_and\_Wound\_Sensitivity\_Data\_Analysis.R

**Description:** R script for preference and wound sensitivity data

#### File: Adcock\_Tucker\_2020\_Conditioning\_Trials\_Data.xlsx

**Description:** Sheet 1 contains data; Sheet 2 is the key explaining each column name 

##### Variables

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#### File: Adcock\_Tucker\_2020\_Preference\_Test\_and\_Wound\_Sensitivity\_Data.xlsx

**Description:** Sheet 1 contains data; Sheet 2 is the key explaining each column name 

##### Variables

*

#### File: Adcock\...