Novel transcriptomic microglia taxonomy across mouse and human pathologies

This archive contains the processed Seurat objects and associated R scripts used to generate all main and extended figures from the manuscript: Chhatbar et al. The data includes single-cell transcriptomic or spatial transcriptomics profiles of human brain immune cells, focusing on microglia across multiple brain regions and neurological conditions across two species, human and mouse. Each .rds file corresponds to a specific figure (or panel group), and accompanying R scripts reproduce the individual plots used to build the figures. Each figure's individual plots can be reproduced and saved using .R scripts. Final composite figures in the paper were assembled in Adobe Illustrator from these components.本归档文件包含经处理的Seurat（Seurat）对象及配套R脚本，可用于复现Chhatbar等人所著论文中的所有主图与扩展图。 本数据集涵盖人类与小鼠两个物种的大脑免疫细胞单细胞转录组或空间转录组图谱，研究聚焦于多个脑区及多种神经系统疾病状态下的小胶质细胞。每个.rds文件对应一张特定图片（或面板组），配套的R脚本可复现用于构建该图片的独立绘图元素。 可通过.R脚本复现并导出每张图片的独立绘图组件，论文中的最终合成图片均由这些组件在Adobe Illustrator中组装完成。