Additional file 1 of Seven key hub genes identified by gene co-expression network in cutaneous squamous cell carcinoma

Additional file 1: Supplementary Table 1. Genes in the module 5 for cSCC in the GSE45216–98774 dataset. Supplementary Table 2. Genes in the module 23 for AK in the GSE45216–98774 dataset. Supplementary Table 3. Genes in the module 9 for normal sample in the GSE45216–98774 dataset. Supplementary Table 4. Genes in the module 5 for cSCC in the GSE108008 dataset. Supplementary Table 5. Genes in the module 10 for AK in the GSE108008 dataset. Supplementary Table 6. Genes in the module 7 for normal sample in the GSE108008 dataset. Supplementary Table 7. Overrepresented GO terms in the module 5 relevant for cSCC in the GSE45216–98774 dataset. Supplementary Table 8. KEGG functional enrichment of genes in the module 5 relevant for cSCC in the GSE45216–98774 dataset. Supplementary Table 9. KEGG functional enrichment of genes in the module 23 relevant for AK in the GSE45216–98774 dataset. Supplementary Table 10. Overrepresented GO terms in the module 9 relevant for normal tissue in the GSE45216–98774 dataset. Supplementary Table 11. KEGG functional enrichment of genes in the module 9 relevant for normal tissue in the GSE45216–98774 dataset. Supplementary Table 12. Overrepresented GO terms in the module 5 relevant for cSCC in the GSE108008 dataset. Supplementary Table 13. KEGG functional enrichment of genes in the module 5 relevant for cSCC in the GSE108008 dataset. Supplementary Table 14. Overrepresented GO terms in the module 10 relevant for AK in the GSE108008 dataset. Supplementary Table 15. KEGG functional enrichment of genes in the module 10 relevant for AK in the GSE108008 dataset. Supplementary Table 16. Overrepresented GO terms in the module 7 relevant for normal tissue in the GSE108008 dataset. Supplementary Table 17. KEGG functional enrichment of genes in the module 7 relevant for normal tissue in the GSE108008 dataset. Supplementary Table 18. Differentially expressed genes when cSCC compared with AK samples in dataset GSE45216–98774. Supplementary Table 19. Differentially expressed genes when AK compared with normal samples in dataset GSE45216–98774. Supplementary Table 20. Differentially expressed genes when cSCC compared with AK samples in dataset GSE108008. Supplementary Table 21. Differentially expressed genes when AK compared with normal samples in dataset GSE108008. Supplementary Table 22. Differential expression in 21 different TCGA cancer types. Supplementary Table 23. Association of hub gene expression with patient overall survival for different cancer types.

附加文件1：
补充表1：GSE45216–98774数据集中与皮肤鳞状细胞癌（cutaneous squamous cell carcinoma, cSCC）相关的第5模块基因
补充表2：GSE45216–98774数据集中与光化性角化病（actinic keratosis, AK）相关的第23模块基因
补充表3：GSE45216–98774数据集中与正常样本相关的第9模块基因
补充表4：GSE108008数据集中与cSCC相关的第5模块基因
补充表5：GSE108008数据集中与AK相关的第10模块基因
补充表6：GSE108008数据集中与正常样本相关的第7模块基因
补充表7：GSE45216–98774数据集中与cSCC相关的第5模块显著富集的基因本体（Gene Ontology, GO）术语
补充表8：GSE45216–98774数据集中与cSCC相关的第5模块基因的京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）功能富集分析结果
补充表9：GSE45216–98774数据集中与AK相关的第23模块基因的KEGG功能富集分析结果
补充表10：GSE45216–98774数据集中与正常组织相关的第9模块显著富集的GO术语
补充表11：GSE45216–98774数据集中与正常组织相关的第9模块基因的KEGG功能富集分析结果
补充表12：GSE108008数据集中与cSCC相关的第5模块显著富集的GO术语
补充表13：GSE108008数据集中与cSCC相关的第5模块基因的KEGG功能富集分析结果
补充表14：GSE108008数据集中与AK相关的第10模块显著富集的GO术语
补充表15：GSE108008数据集中与AK相关的第10模块基因的KEGG功能富集分析结果
补充表16：GSE108008数据集中与正常组织相关的第7模块显著富集的GO术语
补充表17：GSE108008数据集中与正常组织相关的第7模块基因的KEGG功能富集分析结果
补充表18：GSE45216–98774数据集中cSCC样本与AK样本比较得到的差异表达基因
补充表19：GSE45216–98774数据集中AK样本与正常样本比较得到的差异表达基因
补充表20：GSE108008数据集中cSCC样本与AK样本比较得到的差异表达基因
补充表21：GSE108008数据集中AK样本与正常样本比较得到的差异表达基因
补充表22：21种癌症基因组图谱（The Cancer Genome Atlas, TCGA）癌症类型中的基因差异表达情况
补充表23：不同癌症类型中枢纽基因表达与患者总生存期的关联情况