Performance of the models.

χ2 = Chi-Square.P values vs Model 1 (Clinical).AIC = Akaike information criterion; BIC = Bayesian information criterion; HL = Hosmer–Lemeshow test; hs-cTnT, = high-sensitivity circulating troponin T;ST2 = high-sensitivity soluble ST2; IDI = integrated discrimination improvement; NRI = net reclassification improvement. NT-proBNP = N-terminal pro-brain natriuretic peptide.Model 1 (Clinical) = Age, Female, NYHA functional class (as I−II vs III−IV), LVEF (as ≥ vs Hemoglobin, Furosemide-equivalent doses treatment as 0, ≤40 mg/day and >40 mg/day or Torasemide as 0, ≤10 mg/day and >10 mg/day),ACEI or ARB treatment, beta-blocker treatment, statin treatment.Model 2 = Model 1+NT-proBNP.Model 3 = Model 1+hs-cTnT.Model 4 = Model 1+ST2.Model 5 = Model 1+NT-proBNP+ST2.Model 6 = Model 1+NT-proBNP+hs-cTnT.Model 7 = Model 1+hs-cTNT+ST2.Model 8 = Model 1+NT-proBNP+hs-cTNT.