Genomic and Clinical Findings in Myeloid Neoplasms with PDGFRB Rearrangement [seq]

Here we characterized a series of 14 cases with myeloid neoplasms using cytogenetic, single nucleotide polymorphism array, and next generation sequencing. Sequencing analysis of thirty genes, recurrently mutated in myeloid malignancies and included in the Myeloid Solution SOPHiA GENETICS (Saint‐Sulpice, Switzerland), was performed on cases with 5q32/PDGFRB involvement. 13 cases were investigated at diagnosis and in 8 cases material from remission was also analyzed.