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TIP60 represses activation of endogenous retroviral elements

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NIAID Data Ecosystem2026-04-25 收录
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We found that the loss of TIP60 de-represses retrotransposon elements genome-wide, which in turn activate the cellular response to pathogens mediated by STING, culminating in an induction of Interferon Regulatory Factor 7 (IRF7) and associated inflammatory response.

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2019-12-31
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