Summary of longitudinal changes in inflammatory protein levels between cognitive decline groups as measured by ADAS-cog.

The relationship between change in cytokine levels over one year and AD cognitive decline group was assessed by mixed effect model adjusting for age, gender, APOε4 allelle, collection site and disease duration. Slow indicates slow decliner. Inter indicates intermediate decliner. Fast indicates fast decliner. Key: Beta = regression coefficient (slope) on transformed data; 95%CI = 95% confidence interval;N = number of sample; ¥ - coefficients represent the difference in the slopes for the given cytokine between cognitive decline groups across the two time points (i.e. interaction between time and the rate of decline groups).
*p<0.05.