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Field data for: Enterovirus sequence data obtained from primate samples in Central Africa suggest a high prevalence of enteroviruses with possible zoonotic potential

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Zenodo2021-09-25 更新2026-05-25 收录
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Enteroviruses infect humans and animals, can cause disease, and some may be transmitted across species barriers. We collected different types of samples from various species of Central African wildlife, including data on sampling location and tested the samples for the presence of Enterovirus RNA using a family level PCR. Specimen collection was approved by an Institutional Animal Care and Use Committee (IACUC) of the University of California Davis, and the Governments of Cameroon and the Democratic Republic of the Congo. Enterovirus RNA was detected in samples from 17 primates and 2 rodents. Some sequences were very similar while others were dissimilar to known species, highlighting the unexplored enterovirus diversity in wildlife. The samples and filed data were collected by field ecologists as part of the USAID funded PREDICT project (https://ohi.vetmed.ucdavis.edu/programs-projects/predict-project) and screened for enterovirus RNA using consensus PCR. Maps were generated using basic maps from Paintmaps (http://www.paintmaps.com), a free tool for educational and academic use. The dataset contains the metadata on enterovirus screening among wildlife in Cameroon and the Democratic Republic of the Congo from 2003-2014 as part of the USAID funded PREDICT project. Please refer to the article for more information on methods and references.

肠道病毒(Enterovirus)可感染人类与动物并引发疾病,部分毒株可跨物种屏障传播。本研究从中非各类野生动物物种中采集了多种类型的样本,记录了采样地点信息,并采用科水平聚合酶链式反应(PCR)检测样本中是否存在肠道病毒核糖核酸(RNA)。样本采集工作已获得加州大学戴维斯分校动物护理与使用委员会(IACUC),以及喀麦隆与刚果民主共和国政府的批准。研究人员在17只灵长类动物与2只啮齿类动物的样本中检测到了肠道病毒RNA。部分序列与已知肠道病毒毒株高度相似,而另一些则差异显著,这凸显了野生动物中尚未被探明的肠道病毒多样性。本研究的样本与野外数据由野外生态学家采集,作为美国国际开发署(USAID)资助的PREDICT项目的一部分(https://ohi.vetmed.ucdavis.edu/programs-projects/predict-project),并通过通用型PCR对样本进行肠道病毒RNA筛查。研究使用Paintmaps(http://www.paintmaps.com)提供的基础地图生成了相关分布图,该工具为面向教育与学术用途的免费制图工具。本数据集包含2003年至2014年间,在美国国际开发署资助的PREDICT项目框架下,于喀麦隆与刚果民主共和国境内开展的野生动物肠道病毒筛查相关元数据。如需了解实验方法与参考文献的更多细节,请参阅相关研究论文。

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2021-09-25
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