Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00230
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Human Deoxyhypusine Synthase Fragment Screening Campaign - ligand VT00230 Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(4-fluorophenyl)-1~{H}-pyrazol-3-amine, Deoxyhypusine synthase, ... Authors: Wilk, P, Wator-Wilk, E, Krojer, T, Grudnik, P. Deposit date: 2025-02-15 Release date: 2026-01-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystallographic fragment screening supports tool compound discovery and reveals conformational flexibility in human deoxyhypusine synthase. Commun Chem, 9, 2026
人脱氧羟丁氨酸合酶（Human Deoxyhypusine Synthase）片段筛选项目——配体VT00230描述符：(4R)-2-甲基戊烷-2,4-二醇、4-(4-氟苯基)-1H-吡唑-3-胺、脱氧羟丁氨酸合酶…… 作者：Wilk P、Wator-Wilk E、Krojer T、Grudnik P。入库日期：2025-02-15；发布日期：2026-01-21；最后修改日期：2026-02-18；实验方法：X射线衍射（1.43埃）；引用文献：晶体学片段筛选助力工具化合物发现，揭示人脱氧羟丁氨酸合酶的构象柔性。《Communications Chemistry》，9卷，2026年
创建时间：
2025-02-15
