Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

Destruction of cartilage and bone are hallmarks of human rheumatoid arthritis (RA), and controlling these erosive processes is the most challenging objective in the...软骨与骨组织破坏是人类类风湿性关节炎（RA）的标志性病理特征，而对这类侵蚀性病理进程的有效管控，乃是该疾病临床干预与研究中最具挑战性的目标