P38 kinase crystal structure in complex with RO7125
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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P38 kinase crystal structure in complex with RO7125 Descriptor: 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidine, Mitogen-activated protein kinase 14 Authors: Kuglstatter, A, Ghate, M. Deposit date: 2008-12-17 Release date: 2009-12-22 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
与RO7125形成复合物的P38激酶（P38 kinase）晶体结构，配体描述为3-[2-氯-5-(甲基磺酰基)苯基]-6-(2,4-二氟苯氧基)-1H-吡唑并[3,4-d]嘧啶，靶标为丝裂原活化蛋白激酶14（Mitogen-activated protein kinase 14）；作者：Kuglstatter, A、Ghate, M.；沉积日期：2008-12-17；发布日期：2009-12-22；最后修改日期：2023-09-06；解析方法：X射线衍射（X-RAY DIFFRACTION，分辨率2埃）；引用文献：《Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity》（待发表）
创建时间：
2008-12-17
