遇见数据集

ROC_all SINTEF workflow results with CASCADE topology

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Zenodo2020-12-24 更新2026-05-25 收录
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This dataset has the input data + result dataset that was the product of using the <strong>DrugLogics</strong> computational pipeline with the <strong>rbbt</strong> workflow system to predict synergistic drug combinations across 8 cell lines that were also tested in SINTEF. The <strong>CASCADE topology</strong> was used and the logical models were trained to a <strong>steady state activity profile </strong>that was derived using the <strong>PARADIGM tool</strong> and input from the<strong> CCLE</strong>.

本数据集涵盖输入数据与结果数据集,其为借助<strong>DrugLogics计算流水线(DrugLogics computational pipeline)</strong>与<strong>rbbt工作流系统(rbbt workflow system)</strong>,针对8种细胞系预测<strong>协同药物组合(synergistic drug combinations)</strong>的生成成果;上述细胞系亦在SINTEF机构中完成了相关测试。本研究采用了<strong>CASCADE拓扑结构(CASCADE topology)</strong>,并将逻辑模型训练至由<strong>PARADIGM工具(PARADIGM tool)</strong>推导得到、且输入数据来源于<strong>CCLE(Cancer Cell Line Encyclopedia)</strong>的<strong>稳态活性谱(steady state activity profile)</strong>。

提供机构:
Zenodo
创建时间:
2019-10-28
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