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The siRNA seed region is divided into two functionally different domains in RNA interference in response to 2´-OMe modifications. The siRNA seed region is divided into two functionally different domains in RNA interference in response to 2´-OMe modifications

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA778247
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资源简介:
To investigate effects of siRNA with 2'-O-methyl (2'-Ome) modifications on genome-wide off-targetat, we analyzed gene expression profile of HeLa cells transfected by their siRNAs. Overall design: Total RNAs were extracted from HeLa cells transfected by unmodified or 2'-O-methyl (2'-Ome) modified siRNA and performed microarray analysis.
创建时间:
2021-11-05
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