Investigating resistance mechanisms to CB-839 in renal cell carcinoma using a whole-genome CRISPR/Cas9 approach (Thesis data)
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下载链接：
https://research-portal.st-andrews.ac.uk/en/datasets/investigating-resistance-mechanisms-to-cb-839-in-renal-cell-carci
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资源简介：
this thesis describes a genome-scale CRISPR/Cas9 screen approach in a cell culture model of ccRCC (786-0 cell line) to identify candidate genes (hits), which when knocked down confer resistance to CB-839. Next generation sequencing data analysis of drug-selected sgRNA library representation from two timepoints was performed using the MAGeCKFlute bioinformatics workflow.
提供机构：
University of St Andrews
创建时间：
2021-11-12
