BIOGRID CURATED DATA FOR BRE2 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for BRE2 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Subunit of COMPASS (Set1C) complex; COMPASS methylates Lys4 of histone H3 and functions in silencing at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction (SDI) domain that mediates binding to Sdc1p; similar to trithorax-group protein ASH2L

BRE2（酿酒酵母S288c）的蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）精心整理；定义：COMPASS（Set1C）复合体亚基；COMPASS复合体催化组蛋白H3的赖氨酸4位甲基化，并在端粒的沉默作用中发挥作用；具有C端Sdc1 Dpy-30相互作用（SDI）结构域，介导与Sdc1p的结合；与三价组蛋白蛋白家族ASH2L相似。