Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
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Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) Descriptor: FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... Authors: Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. Deposit date: 2018-11-01 Release date: 2019-04-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.1 Å) Cite: SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. J.Cell Biol., 218, 2019
人类Scribble蛋白PDZ1结构域(PDZ1 domain)与含Src同源3结构域(Src Homology 3 domain, SH3)的鸟苷酸交换因子(guanine nucleotide exchange factor, GEF)SGEF的内部PDZ结合基序形成复合物的晶体结构 样品描述:甲酸、Scribble同源蛋白、Rho鸟苷酸交换因子26…… 作者:Sun, Y.J.、Hou, T.、Gakhar, L.、Fuentes, E.J. 存入日期:2018年11月1日 发布日期:2019年4月10日 最后更新日期:2024年11月13日 实验方法:X射线衍射(分辨率1.1埃) 引用文献:SGEF与Scribble和Dlg1形成复合物并调控上皮连接与细胞收缩性,《细胞生物学杂志》,2019年,第218卷



