Prevalence of abnormalities detected by each FISH marker among the primary and the metastatic or castration-resistant prostate cancer (Met/CRPC) patients.

1Average AR per nucleus ≥1.5 but <2.
2Average AR per nucleus ≥2 but average AR/X ratio<2.
3Average AR/X ratio≥2.
4Average PTEN/CEP10 ratio≤0.75 but >0.2.
5Average PTEN/CEP10 ratio≤0.2.
6Wald tests of abnormal vs. normal for primary vs. CRPC, generalized estimating equations (GEE) with independence autocorrelation, adjusting for rapid autopsy vs xenograft sample for CRPC. Likelihood ratio test for AR (without adjustment for autocorrelation), since no primary samples had abnormal AR.
7Wald tests of abnormal vs. normal for primary vs. CRPC, logistic regression adjusting for rapid autopsy vs xenograft sample for CRPC. Likelihood ratio test for AR, since no primary samples had abnormal AR.