The effect of Stage I-II periodontitis on the mechanical, structural and biological properties of leukocyte andplatelet-rich fibrin

This study aimed to compare the mechanical, biological and structural properties of leukocyte and platelet-rich fibrin (L-PRF) membrane in periodontally healthy and periodontitis patients. A total of 30 individuals, including 17 males and 13 females, with a median age of 41 years were divided into two groups as periodontally healthy (control group) and periodontitis (test group). Methodology: Blood samples were collected and centrifuged at 2700 rpm for 12 minutes. Tensile test was performed to determine the mechanical properties of L-PRF membranes. Elasticity (E)-modulus, tensile strength and stretch at rupture were calculated. Platelet and leucocyte counts and ratios were calculated. Fibril thickness and density were evaluated by scanning electron microscopy imaging.